Dst^em13Dcr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dst^em13Dcr
• Name: dystonin; endonuclease-mediated mutation 13, Derry C Roopenian
• MGI ID: MGI:6258920
• Gene: Dst Location: Chr1:33947306-34347742 bp, + strand Genetic Position: Chr1, 12.91 cM
• Alliance: Dst^em13Dcr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 endonuclease mediated genome editing is used to introduce a 1016 bp deletion in exon 23, which is specific for the epidermis isoform Dst-e. and causes a frame-shift (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dst Mutation: 558 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)