Igdmrem1Takas
Endonuclease-mediated Allele Detail
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Symbol: |
Igdmrem1Takas |
Name: |
intergenic germline-derived differentially methylated region; endonuclease-mediated mutation 1, Shuji Takada |
MGI ID: |
MGI:6258427 |
Synonyms: |
IG-DMRDeltaRep |
Gene: |
Igdmr Location: unknown Genetic Position: Chr12, Syntenic
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Alliance: |
Igdmrem1Takas page
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Allele Type: |
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Endonuclease-mediated (Not Applicable) |
Mutation: |
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Intergenic deletion
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Mutation details: This differentially methylated region between Dlk1 and Gtl2 was targeted with four transcription activator-like effector-based nuclease (TALEN) mRNAs flanking the 216 bp CpG-rich tandem repeat array in the center. Line T334 showed a 336 bp deletion that includes the entire repeat sequence.
(J:266963)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Igdmr Mutation: |
2 strains or lines available
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Original: |
J:266963 Saito T, et al., A tandem repeat array in IG-DMR is essential for imprinting of paternal allele at the Dlk1-Dio3 domain during embryonic development. Hum Mol Genet. 2018 Sep 15;27(18):3283-3292 |
All: |
1 reference(s) |
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