Klf4^em1Holi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klf4^em1Holi
• Name: Kruppel-like transcription factor 4 (gut); endonuclease-mediated mutation 1, Hongliang Li
• MGI ID: MGI:6258424
• Synonyms: KLF4^flox
• Gene: Klf4 Location: Chr4:55527143-55532466 bp, - strand Genetic Position: Chr4, 29.76 cM
• Alliance: Klf4^em1Holi page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology was used to flank exon 2 with loxP sites. (J:266946)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf4 Mutation: 25 strains or lines available

References

• Original: J:266946 Cheng WL, et al., Interferon Regulatory Factor 4 Inhibits Neointima Formation by Engaging Kruppel-Like Factor 4 Signaling. Circulation. 2017 Oct 10;136(15):1412-1433
• All: 1 reference(s)