Tg(Myh6/tetO-Thbs3)1Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6/tetO-Thbs3)1Jmol
• Name: transgene insertion 1, Jeffery Molkentin
• MGI ID: MGI:6258266
• Transgene: Tg(Myh6/tetO-Thbs3)1Jmol Location: unknown
• Alliance: Tg(Myh6/tetO-Thbs3)1Jmol page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Myh6/tetO-Thbs3)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Thbs3 (MGI:98739)

• Tg(Myh6/tetO-Thbs3)1Jmol expression driven by 2 genes
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)
  Not Specified	tetO

• Mutation details: Full-length mouse Thbs3 cDNA was placed under the regulatory control of the mouse Myh6/tetO minimal promoter. (J:271593)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:271593 Schips TG, et al., Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019 Jan 8;10(1):76
• All: 2 reference(s)