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Tg(Thy1-EYFP/difopein)142Yzho
Transgene Detail
Summary
Symbol: Tg(Thy1-EYFP/difopein)142Yzho
Name: transgene insertion 142, Yi ZhouYi Zhou
MGI ID: MGI:6257912
Transgene: Tg(Thy1-EYFP/difopein)142Yzho  Location: unknown  
Alliance: Tg(Thy1-EYFP/difopein)142Yzho page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsThe mouse promoter drives neuronal expression of a fusion gene expressing the EYFP yellow fluorescent protein fused to the N-terminus of difopein (a dimeric-Ywhaq-inhibitor). Transgene expressing line 142, with minimal expression in pyramidal neurons in the CA1 subregion of the hippocampus and expression in only a fraction of the CA3 neurons, was chosen for further study. (J:210442)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:210442 Qiao H, et al., 14-3-3 proteins are required for hippocampal long-term potentiation and associative learning and memory. J Neurosci. 2014 Apr 2;34(14):4801-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory