Akr1b1^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Akr1b1^em1(IMPC)Bay
• Name: aldo-keto reductase family 1 member B; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257794
• Gene: Akr1b1 Location: Chr6:34280865-34294424 bp, - strand Genetic Position: Chr6, 14.87 cM, cytoband B1
• Alliance: Akr1b1^em1(IMPC)Bay page
• IMPC: Akr1b1 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 Protein and 4 guide sequences GGTGGCCAGGCTCCGAAGCGGGG, TCGTCATGATTGGAGCTGTGAGG, ATGGGAATCCTCGTCATGATTGG, CCTAGGAACATCAACCTCCCAGG, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akr1b1 Mutation: 27 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)