Prkra^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prkra^em2(IMPC)H
• Name: protein kinase, interferon inducible double stranded RNA dependent activator; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6257692
• Gene: Prkra Location: Chr2:76460242-76478359 bp, - strand Genetic Position: Chr2, 45.07 cM
• Alliance: Prkra^em2(IMPC)H page
• IMPC: Prkra gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and guides with spacer sequences AATCTGGTAGTTAACGGTAA, CGTTAACTACCAGATTTAAT, TAGCTAACGTGGATAGATAA, and TGCCTGCTTAGCTTAAACCA that targeted exon(s) ENSMUSE00000165562.2. This resulted in deletion(s) of 650 bp (location: Chr2:76473396-76474045; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkra Mutation: 25 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)