Nupr1^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nupr1^em1(IMPC)Bay
• Name: nuclear protein transcription regulator 1; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257649
• Gene: Nupr1 Location: Chr7:126222418-126224642 bp, - strand Genetic Position: Chr7, 69.21 cM, cytoband F4
• Alliance: Nupr1^em1(IMPC)Bay page
• IMPC: Nupr1 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and 4 guides with spacer sequences CCCGCCAGGGCTAGGGCGGT, CTAAACCTAGAGGATGAAGA, and CTAGCCCTGGCGGGCATGAG that targeted exon(s) ENSMUSE00000358864.4 ENSMUSE00000796095.2. This resulted in deletion(s) of 445 bp (location: Chr7:126224124-126224568; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nupr1 Mutation: 11 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)