Serpina3j^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Serpina3j^em1(IMPC)Bay
• Name: serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257605
• Gene: Serpina3j Location: Chr12:104280812-104286984 bp, + strand Genetic Position: Chr12, 53.92 cM, cytoband F1
• Alliance: Serpina3j^em1(IMPC)Bay page
• IMPC: Serpina3j gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences TCTGAGAATATCGACTTTAT and TGCTGTCCAGAGGACACATT that targeted exon(s) ENSMUSE00000682191.3 ENSMUSE00000682194.3 ENSMUSE00001028671.2 ENSMUSE00001084184.2. This resulted in deletion(s) of 5236 bp (location: Chr12:104280842-104286077; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Serpina3j Mutation: 25 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)