Tm2d2^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tm2d2^em1(IMPC)Bay
• Name: TM2 domain containing 2; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6257594
• Gene: Tm2d2 Location: Chr8:25507227-25513276 bp, + strand Genetic Position: Chr8, 13.7 cM, cytoband A3
• Alliance: Tm2d2^em1(IMPC)Bay page
• IMPC: Tm2d2 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences AAGAAGCCTGTCGAAAAGAA, AGTAAACCTTTCTTTTCGAC, GCTTGGCTAGAGGTACCAGT, and GTTACTTTGAAAGGGGCGCT that targeted exon(s) ENSMUSE00000254776.4 ENSMUSE00001388902.2. This resulted in deletion(s) of 439 bp (location: Chr8:25510277-25510715; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tm2d2 Mutation: 15 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)