Washc5^tm1.1Ccrs
Targeted Allele Detail

Summary

• Symbol: Washc5^tm1.1Ccrs
• Name: WASH complex subunit 5; targeted mutation 1.1, Christoph S Clemen and Rolf Schroder
• MGI ID: MGI:6246601
• Synonyms: Str^N471D, Stru^tm1.1Ccrs
• Gene: Washc5 Location: Chr15:59203846-59246016 bp, - strand Genetic Position: Chr15, 25.17 cM
• Alliance: Washc5^tm1.1Ccrs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: An N471D mutation (AAT to GAC) was inserted at position 1411 to 1413 and a floxed neo cassette was also inserted via homologous recombination. Cre-mediated recombination removed the neo cassette. (J:265574)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Washc5 Mutation: 56 strains or lines available

References

• Original: J:265574 Song L, et al., Expression of N471D strumpellin leads to defects in the endolysosomal system. Dis Model Mech. 2018 Sep 13;11(9):dmm033449
• All: 1 reference(s)