Ffar4^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Ffar4^tm1.2Mrl
• Name: free fatty acid receptor 4; targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6201742
• Synonyms: Gpr120^tm1.2Mrl
• Gene: Ffar4 Location: Chr19:38085527-38102711 bp, + strand Genetic Position: Chr19, 32.73 cM
• Alliance: Ffar4^tm1.2Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265430
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and approx. 1.5 kb of sequence upstream of exon 1 were floxed. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the floxed exons. (J:166124)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar4 Mutation: 21 strains or lines available

References

• Original: J:265430 Ho JD, et al., Structural basis for GPR40 allosteric agonism and incretin stimulation. Nat Commun. 2018 Apr 25;9(1):1645
• All: 9 reference(s)