Gys2^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Gys2^m3Btlr
• Name: glycogen synthase 2; mutation 3, Bruce Beutler
• MGI ID: MGI:6200366
• Synonyms: candy_corn
• Gene: Gys2 Location: Chr6:142368339-142418835 bp, - strand Genetic Position: Chr6, 74.04 cM
• Alliance: Gys2^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 142,456,333 (v38) on chromosome 6, or base pair 16,798 in the GenBank genomic region NC_000072 encoding Gys2. The mutation corresponds to residue 1,087 in the mRNA sequence NM_145572 within exon 5 of 17 total exons. The mutation results in a glutamic acid (E) to glycine (G) substitution at position 260 (E260G) in the GYS2 protein. (J:265258)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gys2 Mutation: 45 strains or lines available

References

• Original: J:265258 Turer E, et al., Mutagenetix entry for candy_corn. MGI Direct Data Submission. 2018
• All: 1 reference(s)