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Endonuclease-mediated Allele Detail
Symbol: Asap3em1(IMPC)J
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 3; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6200307
Gene: Asap3  Location: Chr4:135933676-135972527 bp, + strand  Genetic Position: Chr4, 68.34 cM
Alliance: Asap3em1(IMPC)J page
IMPC: Asap3 gene page
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTTGCCCAAAGGGTAGCAG and AGCTGTTGTGAAAGGACCAG, which resulted in a 282 bp deletion beginning at Chromosome 4 position 136,229,360 bp and ending after 136,229,641 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000497964(exon5) and 232 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 141 and early truncation 36 amino acids later. (J:188991)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Asap3 Mutation:  44 strains or lines available
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory