Apbb2^M1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Apbb2^M1Btlr
• Name: amyloid beta precursor protein binding family B member 2; mutation 1, Bruce Beutler
• MGI ID: MGI:6199157
• Synonyms: Dionysis
• Gene: Apbb2 Location: Chr5:66456046-66776127 bp, - strand Genetic Position: Chr5, 34.43 cM
• Alliance: Apbb2^M1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 66,452,250 (v38) on chromosome 5, or base pair 166,568 in the GenBank genomic region NC_000071 encoding Apbb2. The mutation corresponds to residue 624 in the mRNA sequence NM_001201415 within exon 5 of 16 total exons. The mutation results in a methionine (M) to lysine (K) substitution at position 18 (M18K) in the APBB2 protein. (J:265064)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apbb2 Mutation: 65 strains or lines available

References

• Original: J:265064 SoRelle J, et al., Mutagenetix entry for Dionysis. MGI Direct Data Submission. 2018
• All: 1 reference(s)