Tg(tetO-Cxcl1,-EGFP)#Tela
Transgene Detail

Summary

• Symbol: Tg(tetO-Cxcl1,-EGFP)#Tela
• Name: transgene insertion, Thomas E Lane
• MGI ID: MGI:6199148
• Synonyms: pBI-CXCL1
• Transgene: Tg(tetO-Cxcl1,-EGFP)#Tela Location: unknown
• Alliance: Tg(tetO-Cxcl1,-EGFP)#Tela page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(tetO-Cxcl1,-EGFP)#Tela expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cxcl1 (MGI:108068)	inducible, biderectional promoter; mouse cDNA

• Mutation details: A tetracycline response element (TRE) flanked by two minimal CMV promoters (in either transcriptional direction) forms a biderectional tetracycline/doxycycline inducible promoter driving expression of the EGFP fluorescent protein gene in one direction and of the mouse cDNA in the other direction. (J:265048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:265048 Marro BS, et al., Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination. J Immunol. 2016 Feb 15;196(4):1855-64
• All: 2 reference(s)