Adamts20^m8Btlr
Chemically induced Allele Detail

Summary

• Symbol: Adamts20^m8Btlr
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; mutation 8, Bruce Beutler
• MGI ID: MGI:6198347
• Synonyms: wash
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^m8Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to T transversion at base pair 94,347,670 (v38) on chromosome 15, or base pair 84,405 in the GenBank genomic region NC_000081. The mutation corresponds to residue 2,011 in the mRNA sequence NM_177431 (isoform 1) within exon 12 of 39 total exons. The mutation results in substitution of glutamic acid 584 for a premature stop codon (E584*) in both Adamts20 protein variants. (J:264701)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:264701 Reyna C, et al., Mutagenetix entry for wash. MGI Direct Data Submission. 2018
• All: 1 reference(s)