Bag3^rs31544129-T
Allele Detail

Summary

• Symbol: Bag3^rs31544129-T
• Name: BCL2-associated athanogene 3; rs31544129 SNP allele with the T variant
• MGI ID: MGI:6197830
• Synonyms: Bag3^Ile81
• Gene: Bag3 Location: Chr7:128125340-128148705 bp, + strand Genetic Position: Chr7, 70.26 cM
• Alliance: Bag3^rs31544129-T page

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Not Applicable
• Mutation: Undefined
• Mutation details: An isoleucine is present at residue 81. This variant has been associated with reduced susceptibility to ischemic limb muscle myopathy in C57BL/6J mice. (J:264518)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bag3 Mutation: 29 strains or lines available

References

• Original: J:264518 McClung JM, et al., BAG3 (Bcl-2-Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy. Circulation. 2017 Jul 18;136(3):281-296
• All: 1 reference(s)