Hoxd4^tm1.1Ddu
Targeted Allele Detail

Summary

• Symbol: Hoxd4^tm1.1Ddu
• Name: homeobox D4; targeted mutation 1.1, Denis Duboule
• MGI ID: MGI:6195735
• Synonyms: HoxD^Del(4)
• Gene: Hoxd4 Location: Chr2:74552322-74559504 bp, + strand Genetic Position: Chr2, 44.13 cM, cytoband D
• Alliance: Hoxd4^tm1.1Ddu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252916
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites were inserted immediately upstream and downstream of the gene. Cre-mediated recombination subsequently deleted the gene, creating a null allele. (J:252916)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd4 Mutation: 10 strains or lines available

References

• Original: J:252916 Zakany J, et al., Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9290-E9299
• All: 1 reference(s)