Stxbp3^tm1.1Adch
Targeted Allele Detail

Summary

• Symbol: Stxbp3^tm1.1Adch
• Name: syntaxin binding protein 3; targeted mutation 1.1, Roberto Adachi
• MGI ID: MGI:6195194
• Synonyms: Munc18-3^F
• Gene: Stxbp3 Location: Chr3:108700496-108747818 bp, - strand Genetic Position: Chr3, 47.73 cM, cytoband F3
• Alliance: Stxbp3^tm1.1Adch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263883
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed and an FRT flanked neo cassette was inserted downstream of exon 2 via homologous recombination. Flp meditated recombination removed the neo cassette. (J:263883)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stxbp3 Mutation: 23 strains or lines available

References

• Original: J:263883 Gutierrez BA, et al., Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem. 2018 May 11;293(19):7148-7159
• All: 3 reference(s)