Peli1^tm1Hlee
Targeted Allele Detail

Summary

• Symbol: Peli1^tm1Hlee
• Name: pellino 1; targeted mutation 1, Ho Lee
• MGI ID: MGI:6195163
• Synonyms: Peli1^tm1Dohc
• Gene: Peli1 Location: Chr11:21041291-21100323 bp, + strand Genetic Position: Chr11, 13.81 cM, cytoband A3.2
• Alliance: Peli1^tm1Hlee page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254231
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 4 was replaced with a puromycin resistance gene cassette. (J:254231)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Peli1 Mutation: 32 strains or lines available

References

• Original: J:254231 Kim D, et al., Cytosolic Pellino-1-Mediated K63-Linked Ubiquitination of IRF5 in M1 Macrophages Regulates Glucose Intolerance in Obesity. Cell Rep. 2017 Jul 25;20(4):832-845
• All: 2 reference(s)