Slc34a2^tm1Nhch
Targeted Allele Detail

Summary

• Symbol: Slc34a2^tm1Nhch
• Name: solute carrier family 34 (sodium phosphate), member 2; targeted mutation 1, Nati Hernando
• MGI ID: MGI:6193664
• Gene: Slc34a2 Location: Chr5:53206695-53229006 bp, + strand Genetic Position: Chr5, 28.92 cM
• Alliance: Slc34a2^tm1Nhch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263741
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 9 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into exon 13 (replacing part of the 3' UTR). This creates a conditional-ready allele with the coding region of exons 10-13 floxed. (J:263741)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc34a2 Mutation: 46 strains or lines available

References

• Original: J:263741 Hernando N, et al., Intestinal Depletion of NaPi-IIb/Slc34a2 in Mice: Renal and Hormonal Adaptation. J Bone Miner Res. 2015 Oct;30(10):1925-37
• All: 1 reference(s)