Panx3^tm1Yoya
Targeted Allele Detail

Summary

• Symbol: Panx3^tm1Yoya
• Name: pannexin 3; targeted mutation 1, Yoshihiko Yamada
• MGI ID: MGI:6189189
• Gene: Panx3 Location: Chr9:37571198-37580518 bp, - strand Genetic Position: Chr9, 20.79 cM
• Alliance: Panx3^tm1Yoya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246895
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced a 2 kb segment of exon 1. Western blot analysis confirmed the absence of protein in tails. (J:246895)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Panx3 Mutation: 23 strains or lines available

References

• Original: J:246895 Ishikawa M, et al., Pannexin 3 and connexin 43 modulate skeletal development through their distinct functions and expression patterns. J Cell Sci. 2016 Mar 01;129(5):1018-30
• All: 3 reference(s)