Mefv^tm1Gne
Targeted Allele Detail

Summary

• Symbol: Mefv^tm1Gne
• Name: Mediterranean fever; targeted mutation 1, Genentech
• MGI ID: MGI:6188631
• Gene: Mefv Location: Chr16:3525082-3535961 bp, - strand Genetic Position: Chr16, 2.18 cM
• Alliance: Mefv^tm1Gne page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263129
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Undefined
• No details are provided.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mefv Mutation: 45 strains or lines available

References

• Original: J:263129 Van Gorp H, et al., Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14384-14389
• All: 8 reference(s)