Csnk1d^em1Hokh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Csnk1d^em1Hokh
• Name: casein kinase 1, delta; endonuclease-mediated mutation 1, Hitoshi Okamura
• MGI ID: MGI:6188301
• Gene: Csnk1d Location: Chr11:120849816-120882156 bp, - strand Genetic Position: Chr11, 84.75 cM, cytoband E2
• Alliance: Csnk1d^em1Hokh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263005
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR-targeting removed 49 bp from the 3'UTR abolishing m6a methylation. (J:263005)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csnk1d Mutation: 15 strains or lines available

References

• Original: J:263005 Fustin JM, et al., Two Ck1delta transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock. Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):5980-5985
• All: 1 reference(s)