Lgals7^tm1Ijmfp
Targeted Allele Detail

Summary

• Symbol: Lgals7^tm1Ijmfp
• Name: lectin, galactose binding, soluble 7; targeted mutation 1, Francoise Poirier
• MGI ID: MGI:6188114
• Synonyms: galectin-7^-
• Gene: Lgals7 Location: Chr7:28563278-28565709 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband A3
• Alliance: Lgals7^tm1Ijmfp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263069
• Parent Cell Line: WW6 (ES Cell)
• Strain of Origin: STOCK 129/Sv and C57BL/6J and SJL

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A neomycin selection cassette replaced exons 2 and 3. RT-PCR analysis on skin RNA showed absence of transcripts in homozygous mice and Western blot analysis on protein extracts prepared from foot pads showed that no detectable protein was expressed from this allele. (J:263069)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lgals7 Mutation: 7 strains or lines available

References

• Original: J:263069 Gendronneau G, et al., Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell. 2008 Dec;19(12):5541-9
• All: 2 reference(s)