Cryga^Secc
Spontaneous Allele Detail

Summary

• Symbol: Cryga^Secc
• Name: crystallin, gamma A; small eye, cataract, closed eyelid
• MGI ID: MGI:6187998
• Gene: Cryga Location: Chr1:65139552-65142532 bp, - strand Genetic Position: Chr1, 32.84 cM
• Alliance: Cryga^Secc page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: The molecular lesion is a single G deletion at coding nucleotide 273 in exon 3 of the gene. The mutation causes a frameshift at the 91st amino acid and disrupt the 3rd and 4th Greek-key motifs of the encoded protein, producing a mutant protein with an unrelated peptide of 75 amino acids at the C-terminus. (J:250425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cryga Mutation: 14 strains or lines available

References

• Original: J:250425 Cheng MH, et al., A gammaA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid. PLoS One. 2016;11(8):e0160691
• All: 1 reference(s)