Abca7^em1Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Abca7^em1Adiuj
• Name: ATP-binding cassette, sub-family A member 7; endonuclease-mediated mutation 1, MODEL-AD Center
• MGI ID: MGI:6187700
• Gene: Abca7 Location: Chr10:79832328-79851406 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Abca7^em1Adiuj page

Mutation origin

• Strain of Origin: B6(SJL)-Apoe^{tm1.1(APOE*4)Adiuj} Trem2^em1Adiuj/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing is used to introduce a 33 bp deletion in exon 32. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abca7 Mutation: 89 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)