Dcaf17^tm1Assi
Targeted Allele Detail

Summary

• Symbol: Dcaf17^tm1Assi
• Name: DDB1 and CUL4 associated factor 17; targeted mutation 1, Abdullah Assiri
• MGI ID: MGI:6164305
• Synonyms: Dcaf17^fl
• Gene: Dcaf17 Location: Chr2:70885672-70929486 bp, + strand Genetic Position: Chr2, 42.38 cM
• Alliance: Dcaf17^tm1Assi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262620
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A FRT/loxP flanked neomycin cassette was inserted upstream of exon 4 in intron 3-4 in an opposite direction in relation to the target gene. A single loxP site was inserted downstream of exon 4. (J:262620)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcaf17 Mutation: 31 strains or lines available

References

• Original: J:262620 Ali A, et al., Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. Sci Rep. 2018 Jun 15;8(1):9202
• All: 1 reference(s)