Rnf128^em1Yic
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf128^em1Yic
• Name: ring finger protein 128; endonuclease-mediated mutation 1, Yingchuan Chen
• MGI ID: MGI:6163987
• Synonyms: Grail KO
• Gene: Rnf128 Location: ChrX:138464089-138573894 bp, + strand Genetic Position: ChrX, 61.35 cM
• Alliance: Rnf128^em1Yic page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 1, resulting in the removal of the first start codon. (J:262525)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf128 Mutation: 11 strains or lines available

References

• Original: J:262525 Liu P, et al., Grail is involved in adipocyte differentiation and diet-induced obesity. Cell Death Dis. 2018 May 9;9(5):525
• All: 4 reference(s)