Npr3^{tm2(cre/GFP)Bzsh}
Targeted Allele Detail

Summary

• Symbol: Npr3^{tm2(cre/GFP)Bzsh}
• Name: natriuretic peptide receptor 3; targeted mutation 1, Bin Zhou
• MGI ID: MGI:6163737
• Synonyms: Npr3-GFP
• Gene: Npr3 Location: Chr15:11839982-11907287 bp, - strand Genetic Position: Chr15, 5.83 cM
• Alliance: Npr3^{tm2(cre/GFP)Bzsh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256775
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Npr3^{tm2(cre/GFP)Bzsh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Npr3 (MGI:97373)

• The targeting construct introduced a 2A sequence and cre/GFP fusion into the last coding exon. (J:256775)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Npr3 (mouse) Summary of all recombinase alleles driven by Npr3. Comparative matrix view of recombinase activities Alliance mouse Npr3 gene page

Expression

In Mice Carrying this Mutation:

28 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npr3 Mutation: 49 strains or lines available

References

• Original: J:256775 Zhang H, et al., Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls. Circ Res. 2016 Jun 10;118(12):1880-93
• All: 1 reference(s)