Nfatc1^tm2(cre)Bzsh
Targeted Allele Detail

Summary

• Symbol: Nfatc1^tm2(cre)Bzsh
• Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; targeted mutation 2, Bin Zhou
• MGI ID: MGI:6163733
• Synonyms: Nfatc1-Cre
• Gene: Nfatc1 Location: Chr18:80649420-80756286 bp, - strand Genetic Position: Chr18, 53.66 cM, cytoband E4
• Alliance: Nfatc1^tm2(cre)Bzsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256775
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Nfatc1^tm2(cre)Bzsh expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nfatc1 (MGI:102469)

• Mutation details: A cassette containing an IRES-cre cDNA sequence and FRT-flanked PGK-hygromycin selection marker was inserted into the 3' UTR. (J:256775)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nfatc1 (mouse) Summary of all recombinase alleles driven by Nfatc1. Comparative matrix view of recombinase activities Alliance mouse Nfatc1 gene page

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfatc1 Mutation: 47 strains or lines available

References

• Original: J:256775 Zhang H, et al., Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls. Circ Res. 2016 Jun 10;118(12):1880-93
• All: 4 reference(s)