Spry4^tm1Hadj
Targeted Allele Detail

Summary

• Symbol: Spry4^tm1Hadj
• Name: sprouty RTK signaling antagonist 4; targeted mutation 1, Anna-Katerina Hadjantonakis
• MGI ID: MGI:6163623
• Synonyms: Spry4^H2B-Venus
• Gene: Spry4 Location: Chr18:38719300-38734400 bp, - strand Genetic Position: Chr18, 20.5 cM
• Alliance: Spry4^tm1Hadj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: KH2 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector containing, from 3' to 5': a single residual FRT site, an Engrailed 2 (En2) intron and H2B/Venus fusion cassette, a Rox-flanked beta-actin-NEO-pA cassette, and a loxP site was inserted upstream of exon 2. A second loxP site was inserted downstream of exon 2. Exon 2 contains the ATG start codon. (J:101977, J:264612)

Expression

In Mice Carrying this Mutation:

280 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spry4 Mutation: 43 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)