Shoc1^tm2Rjpz
Targeted Allele Detail

Summary

• Symbol: Shoc1^tm2Rjpz
• Name: shortage in chiasmata 1; targeted mutation 2, Roberto J Pezza
• MGI ID: MGI:6160879
• Synonyms: Shoc1^hyp
• Gene: Shoc1 Location: Chr4:59043753-59138983 bp, - strand Genetic Position: Chr4, 32.36 cM
• Alliance: Shoc1^tm2Rjpz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262079
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Hypomorph, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ and neomycin resistance cassette replaced exons 2 through 4. (J:262079)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shoc1 Mutation: 53 strains or lines available

References

• Original: J:262079 Guiraldelli MF, et al., SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis. PLoS Genet. 2018 May;14(5):e1007381
• All: 1 reference(s)