Fcgr2b^tm1Cmin
Targeted Allele Detail

Summary

• Symbol: Fcgr2b^tm1Cmin
• Name: Fc receptor, IgG, low affinity IIb; targeted mutation 1, Chieko Mineo
• MGI ID: MGI:6160439
• Synonyms: FcgammaRIIB^fl
• Gene: Fcgr2b Location: Chr1:170786186-170804116 bp, - strand Genetic Position: Chr1, 78.02 cM
• Alliance: Fcgr2b^tm1Cmin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246710
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2 and 3 were floxed. (J:246710)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcgr2b Mutation: 44 strains or lines available

References

• Original: J:246710 Tanigaki K, et al., Endothelial Fcgamma Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice. Diabetes. 2016 Jul;65(7):1996-2005
• All: 4 reference(s)