Tg(Myh6-Fhod3)SRyut
Transgene Detail

Summary

• Symbol: Tg(Myh6-Fhod3)SRyut
• Name: transgene insertion S, Ryu Takeya
• MGI ID: MGI:6160320
• Synonyms: Tg(Fhod3CM-S)
• Transgene: Tg(Myh6-Fhod3)SRyut Location: unknown
• Alliance: Tg(Myh6-Fhod3)SRyut page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Fhod3)SRyut expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fhod3 (MGI:1925847)

• Tg(Myh6-Fhod3)SRyut expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)

• Mutation details: The transgene consists of the mouse cDNA for an alternatively spliced transcript that skips exons 11 and 12 under the control of the mouse alpha myosin heavy chain promoter. RT-PCR confirmed expression from this allele, but at a rate significantly lower than expression from the endogenous gene. (J:262067)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:262067 Matsuyama S, et al., Interaction between cardiac myosin-binding protein C and formin Fhod3. Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4386-E4395
• All: 1 reference(s)