Pax3^Sp-Nag
Spontaneous Allele Detail

Summary

• Symbol: Pax3^Sp-Nag
• Name: paired box 3; splotch-Nag
• MGI ID: MGI:6160243
• Synonyms: dominant white spotting, Dws
• Gene: Pax3 Location: Chr1:78077904-78173771 bp, - strand Genetic Position: Chr1, 39.79 cM
• Alliance: Pax3^Sp-Nag page

Mutation origin

• Strain of Origin: C3.NSY-(D11Mit74-D11Mit229)/Rbrc

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Single point mutation
• Mutation details: A G-to-A missense mutation was identified at coding nucleotide 186 in exon 2 (c.186G>A). This results in a methionine to isoleucine change at codon 62 (p.Met62Ile) in a highly conserved region among vertebrates. (J:250475)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax3 Mutation: 50 strains or lines available

References

• Original: J:250475 Ohno T, et al., A new missense mutation in the paired domain of the mouse Pax3 gene. Exp Anim. 2017 Aug 5;66(3):245-250
• All: 1 reference(s)