Rbck1^tm1.1Hwal
Targeted Allele Detail

Summary

• Symbol: Rbck1^tm1.1Hwal
• Name: RanBP-type and C3HC4-type zinc finger containing 1; targeted mutation 1.1, Henning Walczak
• MGI ID: MGI:6159165
• Synonyms: Hoil-1^fl
• Gene: Rbck1 Location: Chr2:152158254-152174573 bp, - strand Genetic Position: Chr2, 74.83 cM
• Alliance: Rbck1^tm1.1Hwal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261640
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 1 and 2 were floxed and an FRT flanked hygro cassette was inserted in intron 2 via homologous recombination. Flp mediated recombination removed the hygro cassette. (J:261640)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbck1 Mutation: 43 strains or lines available

References

• Original: J:261640 Peltzer N, et al., LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018 May;557(7703):112-117
• All: 2 reference(s)