Bcar3^lr3
Spontaneous Allele Detail

Summary

• Symbol: Bcar3^lr3
• Name: breast cancer anti-estrogen resistance 3; lens rupture 3
• MGI ID: MGI:6158937
• Gene: Bcar3 Location: Chr3:122213406-122323840 bp, + strand Genetic Position: Chr3, 53.41 cM, cytoband G3
• Alliance: Bcar3^lr3 page

Mutation origin

• Strain of Origin: CF1-Bcar3^lr3/TaOpu

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Insertion
• Mutation details: The molecular lesion is a 1-bp insertion of cytosine in exon 7 at position 1452, resulting in a frameshift mutation leading to a premature stop codon and a truncated protein. (J:242526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcar3 Mutation: 68 strains or lines available

References

• Original: J:242526 Kondo T, et al., A novel spontaneous mutation of BCAR3 results in extrusion cataracts in CF#1 mouse strain. Mamm Genome. 2016 Oct;27(9-10):451-9
• All: 1 reference(s)