Tg(Gabra6-rtTA)1Nak
Transgene Detail

Summary

• Symbol: Tg(Gabra6-rtTA)1Nak
• Name: transgene insertion 1, Shigetada Nakanishi
• MGI ID: MGI:6157371
• Synonyms: TeT
• Transgene: Tg(Gabra6-rtTA)1Nak Location: unknown
• Alliance: Tg(Gabra6-rtTA)1Nak page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Transactivator)
• Mutation: Insertion
• Mutation details: Thq transgene is comprised of a truncated Gabra6 gene, the internal ribosomal entry site (IRES) of encephalomyocarditis virus, a cDNA encoding rtTA and an SV40 polyadenylation site. Expression is seem in the cerebellum and granule cells. (J:131250)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:131250 Yamamoto M, et al., Reversible suppression of glutamatergic neurotransmission of cerebellar granule cells in vivo by genetically manipulated expression of tetanus neurotoxin light chain. J Neurosci. 2003 Jul 30;23(17):6759-67
• All: 2 reference(s)