Mymx^em2Eno
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mymx^em2Eno
• Name: myomixer, myoblast fusion factor; endonuclease-mediated mutation 2, Eric N Olson
• MGI ID: MGI:6157040
• Synonyms: Mymx^loxP3,4
• Gene: Mymx Location: Chr17:45911897-45913028 bp, - strand Genetic Position: Chr17, 22.59 cM
• Alliance: Mymx^em2Eno page

Mutation origin

• Strain of Origin: (C57BL/6 x C3H)F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a second loxP site was inserted downstream of exon 3 via CRISPR/Cas9 mediated recombination. (J:261385)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mymx Mutation: 27 strains or lines available

References

• Original: J:261385 Bi P, et al., Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3864-3869
• All: 2 reference(s)