Otulin^em1H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Otulin^em1H
• Name: OTU deubiquitinase with linear linkage specificity; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6156359
• Synonyms: OTULIN-L272P-EM1-B6
• Gene: Otulin Location: Chr15:27606005-27630793 bp, - strand Genetic Position: Chr15, 10.31 cM
• Alliance: Otulin^em1H page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and a guide with spacer sequence TGGTTCCTCAGGAGCTGTTC. This resulted in insertions of 1 bp (location: chr15:27608723; GRCm39), 1 bp (location: chr15:27608727; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Otulin Mutation: 22 strains or lines available

References

• Original: J:155789 Esapa C, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2010
• All: 2 reference(s)