Myc^{em1(IMPC)Kmpc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Myc^{em1(IMPC)Kmpc}
• Name: Myc proto-oncogene, bHLH transcription factor; endonuclease-mediated mutation 1, Korea Mouse Phenotyping Center
• MGI ID: MGI:6156335
• Gene: Myc Location: Chr15:61857240-61862223 bp, + strand Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
• Alliance: Myc^{em1(IMPC)Kmpc} page
• IMPC: Myc gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Korea Mouse Phenotype Consortium using Cas9 and guides with spacer sequences CTGTCCCCGAGCCGCCGCTC and GGACGTAGCGACCGCAACAT that targeted exon(s) ENSMUSE00000858939.2 ENSMUSE00001248962.2 ENSMUSE00001250447.2 ENSMUSE00001251339.2 ENSMUSE00001285920.2. This resulted in deletion(s) of 10 bp (location: Chr15:61859589-61859598; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myc Mutation: 43 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)