Aifm3^{em1(IMPC)Rbrc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aifm3^{em1(IMPC)Rbrc}
• Name: apoptosis-inducing factor, mitochondrion-associated 3; endonuclease-mediated mutation 1, RIKEN BioResource Center
• MGI ID: MGI:6156121
• Gene: Aifm3 Location: Chr16:17307475-17325349 bp, + strand Genetic Position: Chr16, 10.84 cM
• Alliance: Aifm3^{em1(IMPC)Rbrc} page
• IMPC: Aifm3 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: This allele was generated at RIKEN BioResource Research Center using Cas9 and guides with spacer sequences ACCTGTGATCCCGACTTAGG and AGACAAGTGAATGGCCGCGT that targeted exon(s) ENSMUSE00000621182.2 ENSMUSE00001215985.2 ENSMUSE00001228134.2 ENSMUSE00001229093.2 ENSMUSE00001238553.2 ENSMUSE00001238720.2 ENSMUSE00001248892.2 ENSMUSE00001251301.2 ENSMUSE00001273327.2 ENSMUSE00001274444.2 ENSMUSE00001283657.2 ENSMUSE00001284762.2 ENSMUSE00001291107.2 ENSMUSE00001291368.2 ENSMUSE00001303410.2 ENSMUSE00001304194.2. This resulted in deletion(s) of 7232 bp (location: Chr16:17316495-17323726; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aifm3 Mutation: 19 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)