Tm6sf2^em3(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tm6sf2^em3(IMPC)H
• Name: transmembrane 6 superfamily member 2; endonuclease-mediated mutation 3, Harwell
• MGI ID: MGI:6156119
• Gene: Tm6sf2 Location: Chr8:70525574-70532716 bp, + strand Genetic Position: Chr8, 34.15 cM
• Alliance: Tm6sf2^em3(IMPC)H page
• IMPC: Tm6sf2 gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Medical Research Council Harwell using Cas9 and 4 guides with spacer sequences CTTATCCATATTGCTCCCAC, GGCCTGGAATACCATTAGAC, and TCTTGGTTAGGTTTTCTACT that targeted exon(s) ENSMUSE00000235290.4. This resulted in deletion(s) of 400 bp (location: Chr8:70526763-70527162; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tm6sf2 Mutation: 40 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 2 reference(s)