Aicda^tm1Kuro
Targeted Allele Detail

Summary

• Symbol: Aicda^tm1Kuro
• Name: activation-induced cytidine deaminase; targeted mutation 1, Tomohiro Kurosaki
• MGI ID: MGI:6155002
• Synonyms: Aicda^f
• Gene: Aicda Location: Chr6:122530768-122541139 bp, + strand Genetic Position: Chr6, 57.65 cM, cytoband F2
• Alliance: Aicda^tm1Kuro page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241858
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 2 and 3 were flanked by loxP sites. (J:241858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aicda Mutation: 57 strains or lines available

References

• Original: J:241858 Inoue T, et al., The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help. J Exp Med. 2017 Apr 03;214(4):1181-1198
• All: 1 reference(s)