Klf13^tm1Nemr
Targeted Allele Detail

Summary

• Symbol: Klf13^tm1Nemr
• Name: Kruppel-like transcription factor 13; targeted mutation 1, Mona Nemer
• MGI ID: MGI:6154881
• Gene: Klf13 Location: Chr7:63536099-63588663 bp, - strand Genetic Position: Chr7, 34.58 cM
• Alliance: Klf13^tm1Nemr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241786
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2, encoding the 2nd and 3rd zinc fingers, and the entire C-terminus were replaced with a neomycin selection gene. (J:241786)

Expression

In Mice Carrying this Mutation:

77 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf13 Mutation: 47 strains or lines available

References

• Original: J:241786 Darwich R, et al., KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5. Hum Mol Genet. 2017 Mar 01;26(5):942-954
• All: 3 reference(s)