Cma1^tm1Rls
Targeted Allele Detail

Summary

• Symbol: Cma1^tm1Rls
• Name: chymase 1, mast cell; targeted mutation 1, Richard L Stevens
• MGI ID: MGI:6154871
• Synonyms: mMCP-5^-
• Gene: Cma1 Location: Chr14:56178908-56182132 bp, - strand Genetic Position: Chr14, 28.19 cM
• Alliance: Cma1^tm1Rls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241655
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The second intron and most of the third exon were replaced by a neomycin resistance gene. (J:241655)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cma1 Mutation: 26 strains or lines available

References

• Original: J:241655 Stevens RL, et al., Experimental Arthritis Is Dependent on Mouse Mast Cell Protease-5. J Biol Chem. 2017 Mar 31;292(13):5392-5404
• All: 1 reference(s)