Gt(ROSA)26Sor^{tm1(Tlr9)Gbrt}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Tlr9)Gbrt}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Gregory M Barton
• MGI ID: MGI:6154644
• Synonyms: Rosa^lsl-Tlr9
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Tlr9)Gbrt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:258639
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A floxed construct containing an EGFP reporter, neo cassette and stop sequence and an HA tagged Tlr9 cDNA were inserted via homologous recombination. (J:258639)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:258639 Roberts AW, et al., Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells. Immunity. 2017 Nov 21;47(5):913-927.e6
• All: 3 reference(s)