Masp1^em1Or
Endonuclease-mediated Allele Detail

Summary

• Symbol: Masp1^em1Or
• Name: MBL associated serine protease 1; endonuclease-mediated mutation 1, Orly Reiner
• MGI ID: MGI:6154292
• Gene: Masp1 Location: Chr16:23268167-23339565 bp, - strand Genetic Position: Chr16, 14.23 cM, cytoband B2-B3
• Alliance: Masp1^em1Or page

Mutation origin

• Strain of Origin: (BALB/c x C57BL/6J)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 2 bp leading to a frame-shift and premature termination. (J:250385)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Masp1 Mutation: 45 strains or lines available

References

• Original: J:250385 Gorelik A, et al., Developmental activities of the complement pathway in migrating neurons. Nat Commun. 2017 May 02;8:15096
• All: 1 reference(s)